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From residue coevolution to protein conformational ensembles and functional dynamics

The analysis of evolutionary amino acid correlations has recently attracted a surge of renewed interest, also due to their successful use in de novo protein native structure prediction. However, many aspects of protein function, such as substrate binding and product release in enzymatic activity, ca...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Sutto, Ludovico, Marsili, Simone, Valencia, Alfonso, Gervasio, Francesco Luigi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640757/
https://ncbi.nlm.nih.gov/pubmed/26487681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1508584112
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