Opioid-induced Respiratory Depression Is Only Partially Mediated by the preBötzinger Complex in Young and Adult Rabbits In Vivo

BACKGROUND: The preBötzinger Complex (preBC) plays an important role in respiratory rhythm generation. This study was designed to determine whether the preBC mediated opioid-induced respiratory rate depression at clinically relevant opioid concentrations in vivo and whether this role was age-depende...

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Détails bibliographiques
Publié dans:Anesthesiology
Auteurs principaux: Stucke, Astrid G., Miller, Justin R., Prkic, Ivana, Zuperku, Edward J., Hopp, Francis A., Stuth, Eckehard A. E.
Format: Artigo
Langue:Inglês
Publié: 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4639929/
https://ncbi.nlm.nih.gov/pubmed/25751234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000000628
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