Multi-Level Regulation of Opioid-Induced Respiratory Depression

Opioids depress minute ventilation primarily by reducing respiratory rate. This results from direct effects on the preBötzinger Complex as well as from depression of the Parabrachial/Kölliker-Fuse Complex, which provides excitatory drive to preBötzinger Complex neurons mediating respiratory phase-sw...

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Detalhes bibliográficos
Publicado no:Physiology (Bethesda)
Main Authors: Palkovic, Barbara, Marchenko, Vitaliy, Zuperku, Edward J., Stuth, Eckehard A. E., Stucke, Astrid G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2020
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7864237/
https://ncbi.nlm.nih.gov/pubmed/33052772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiol.00015.2020
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