A subregion of the Parabrachial Nucleus partially mediates respiratory rate depression from intravenous remifentanil in young and adult rabbits

BACKGROUND: The efficacy of opioid administration to reduce postoperative pain is limited by respiratory depression. We investigated whether clinically relevant opioid concentrations altered the respiratory pattern in the parabrachial nucleus (PBN), a pontine region contributing to respiratory patte...

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Gepubliceerd in:Anesthesiology
Hoofdauteurs: Miller, Justin R., Zuperku, Edward J., Stuth, Eckehard A.E., Banerjee, Anjishnu, Hopp, Francis A., Stucke, Astrid G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5561451/
https://ncbi.nlm.nih.gov/pubmed/28590302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000001719
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