Pontine μ-opioid receptors mediate bradypnea caused by intravenous remifentanil infusions at clinically relevant concentrations in dogs

Life-threatening side effects such as profound bradypnea or apnea and variable upper airway obstruction limit the use of opioids for analgesia. It is yet unclear which sites containing μ-opioid receptors (μORs) within the intact in vivo mammalian respiratory control network are responsible. The purp...

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Detalhes bibliográficos
Main Authors: Prkic, Ivana, Mustapic, Sanda, Radocaj, Tomislav, Stucke, Astrid G., Stuth, Eckehard A. E., Hopp, Francis A., Dean, Caron, Zuperku, Edward J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545180/
https://ncbi.nlm.nih.gov/pubmed/22875901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00185.2012
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