Molecular insights into the surface-specific arrangement of complement C5 convertase enzymes

BACKGROUND: Complement is a large protein network in plasma that is crucial for human immune defenses and a major cause of aberrant inflammatory reactions. The C5 convertase is a multi-molecular protease complex that catalyses the cleavage of native C5 into its biologically important products. So fa...

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Bibliografski detalji
Izdano u:BMC Biol
Glavni autori: Berends, Evelien T. M., Gorham, Ronald D., Ruyken, Maartje, Soppe, Jasper A., Orhan, Hatice, Aerts, Piet C., de Haas, Carla J. C., Gros, Piet, Rooijakkers, Suzan H. M.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2015
Teme:
Methodology Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4638095/
https://ncbi.nlm.nih.gov/pubmed/26552476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-015-0203-8
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