Structural and functional implications of the complement convertase stabilized by a staphylococcal inhibitor

Activation of the complement system generates potent chemoattractants and opsonizes cells for immune clearance. Short-lived protease complexes cleave complement component C3 into anaphylatoxin C3a and opsonin C3b. Here we report the crystal structure of the C3 convertase formed by C3b and the protea...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Rooijakkers, Suzan H M, Wu, Jin, Ruyken, Maartje, van Domselaar, Robert, Planken, Karel L, Tzekou, Apostolia, Ricklin, Daniel, Lambris, John D, Janssen, Bert J C, van Strijp, Jos A G, Gros, Piet
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2729104/
https://ncbi.nlm.nih.gov/pubmed/19503103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1756
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker