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Structural and functional implications of the complement convertase stabilized by a staphylococcal inhibitor
Activation of the complement system generates potent chemoattractants and opsonizes cells for immune clearance. Short-lived protease complexes cleave complement component C3 into anaphylatoxin C3a and opsonin C3b. Here we report the crystal structure of the C3 convertase formed by C3b and the protea...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2729104/ https://ncbi.nlm.nih.gov/pubmed/19503103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1756 |
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