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Structures of C3b in Complex with Factors B and D Give Insight into Complement Convertase Formation
Activation of the complement cascade induces inflammatory responses and marks cells for immune clearance. In the central complement-amplification step, a complex consisting of surface-bound C3b and factor B is cleaved by factor D to generate active convertases on targeted surfaces. We present crysta...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3087196/ https://ncbi.nlm.nih.gov/pubmed/21205667 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1195821 |
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