Insights into complement convertase formation based on the structure of the factor B-cobra venom factor complex

Immune protection by the complement system critically depends on assembly of C3 convertases on the surface of pathogens and altered host cells. These short-lived protease complexes are formed through pro-convertases, which for the alternative pathway consist of the complement component C3b and the p...

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Detalhes bibliográficos
Main Authors: Janssen, Bert J C, Gomes, Lucio, Koning, Roman I, Svergun, Dmitri I, Koster, Abraham J, Fritzinger, David C, Vogel, Carl-Wilhelm, Gros, Piet
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735180/
https://ncbi.nlm.nih.gov/pubmed/19574954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.184
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