Convertase Inhibitory Properties of Staphylococcal Extracellular Complement-binding Protein

The human pathogen Staphylococcus aureus secretes several complement evasion molecules to combat the human immune response. Extracellular complement-binding protein (Ecb) binds to the C3d domain of C3 and thereby blocks C3 convertases of the alternative pathway and C5 convertases via all complement...

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Main Authors: Jongerius, Ilse, Garcia, Brandon L., Geisbrecht, Brian V., van Strijp, Jos A. G., Rooijakkers, Suzan H. M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Microbiology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865291/
https://ncbi.nlm.nih.gov/pubmed/20304920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.091975
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