Diacetyl Increases Sensory Innervation and Substance P Production in Rat Trachea

Inhalation of diacetyl, a butter flavoring, causes airway responses potentially mediated by sensory nerves. This study examines diacetyl-induced changes in sensory nerves of tracheal epithelium. Rats (n = 6/group) inhaled 0-, 25-, 249-, or 346-ppm diacetyl for 6 hr. Tracheas and vagal ganglia were r...

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Dades bibliogràfiques
Publicat a:Toxicol Pathol
Autors principals: Goravanahally, Madhusudan P., Hubbs, Ann F., Fedan, Jeffery S., Kashon, Michael L., Battelli, Lori A., Mercer, Robert R., Goldsmith, W. Travis, Jackson, Mark C., Cumpston, Amy, Frazer, David G., Dey, Richard D.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4637165/
https://ncbi.nlm.nih.gov/pubmed/23847039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0192623313493689
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