Respiratory and Olfactory Cytotoxicity of Inhaled 2,3-Pentanedione in Sprague-Dawley Rats

Flavorings-related lung disease is a potentially disabling disease of food industry workers associated with exposure to the α-diketone butter flavoring, diacetyl (2,3-butanedione). To investigate the hypothesis that another α-diketone flavoring, 2,3-pentanedione, would cause airway damage, rats that...

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Foilsithe in:Am J Pathol
Main Authors: Hubbs, Ann F., Cumpston, Amy M., Goldsmith, W. Travis, Battelli, Lori A., Kashon, Michael L., Jackson, Mark C., Frazer, David G., Fedan, Jeffrey S., Goravanahally, Madhusudan P., Castranova, Vincent, Kreiss, Kathleen, Willard, Patsy A., Friend, Sherri, Schwegler-Berry, Diane, Fluharty, Kara L., Sriram, Krishnan
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Investigative Pathology 2012
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5691339/
https://ncbi.nlm.nih.gov/pubmed/22894831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.05.021
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