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Diacetyl Increases Sensory Innervation and Substance P Production in Rat Trachea

Inhalation of diacetyl, a butter flavoring, causes airway responses potentially mediated by sensory nerves. This study examines diacetyl-induced changes in sensory nerves of tracheal epithelium. Rats (n = 6/group) inhaled 0-, 25-, 249-, or 346-ppm diacetyl for 6 hr. Tracheas and vagal ganglia were r...

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Detalhes bibliográficos
Publicado no:Toxicol Pathol
Main Authors: Goravanahally, Madhusudan P., Hubbs, Ann F., Fedan, Jeffery S., Kashon, Michael L., Battelli, Lori A., Mercer, Robert R., Goldsmith, W. Travis, Jackson, Mark C., Cumpston, Amy, Frazer, David G., Dey, Richard D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4637165/
https://ncbi.nlm.nih.gov/pubmed/23847039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0192623313493689
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