Practical impacts of genomic data “cleaning” on biological discovery using surrogate variable analysis

BACKGROUND: Genomic data production is at its highest level and continues to increase, making available novel primary data and existing public data to researchers for exploration. Here we explore the consequences of “batch” correction for biological discovery in two publicly available expression dat...

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Bibliographic Details
Published in:BMC Bioinformatics
Main Authors: Jaffe, Andrew E., Hyde, Thomas, Kleinman, Joel, Weinbergern, Daniel R., Chenoweth, Joshua G., McKay, Ronald D., Leek, Jeffrey T., Colantuoni, Carlo
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4636836/
https://ncbi.nlm.nih.gov/pubmed/26545828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0808-5
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