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Removing batch effects for prediction problems with frozen surrogate variable analysis

Batch effects are responsible for the failure of promising genomic prognostic signatures, major ambiguities in published genomic results, and retractions of widely-publicized findings. Batch effect corrections have been developed to remove these artifacts, but they are designed to be used in populat...

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書誌詳細
主要な著者: Parker, Hilary S., Corrada Bravo, Héctor, Leek, Jeffrey T.
フォーマット: Artigo
言語:Inglês
出版事項: PeerJ Inc. 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4179553/
https://ncbi.nlm.nih.gov/pubmed/25332844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.561
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