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Capturing Heterogeneity in Gene Expression Studies by Surrogate Variable Analysis

It has unambiguously been shown that genetic, environmental, demographic, and technical factors may have substantial effects on gene expression levels. In addition to the measured variable(s) of interest, there will tend to be sources of signal due to factors that are unknown, unmeasured, or too com...

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Detalhes bibliográficos
Main Authors: Leek, Jeffrey T, Storey, John D
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1994707/
https://ncbi.nlm.nih.gov/pubmed/17907809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0030161
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