Translocation-coupled DNA cleavage by the Type ISP restriction-modification enzymes

Endonucleolytic double-strand DNA break production requires separate strand cleavage events. Although catalytic mechanisms for simple dimeric endonucleases are available, there are many complex nuclease machines which are poorly understood in comparison. Here we studied the single polypeptide Type I...

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Gepubliceerd in:Nat Chem Biol
Hoofdauteurs: Chand, Mahesh Kumar, Nirwan, Neha, Diffin, Fiona M., van Aelst, Kara, Kulkarni, Manasi, Pernstich, Christian, Szczelkun, Mark D., Saikrishnan, Kayarat
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4636054/
https://ncbi.nlm.nih.gov/pubmed/26389736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1926
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