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Cutting Edge: Inhibiting TBK1 by Compound II Ameliorates Autoimmune Disease in Mice

TANK-binding kinase 1 (TBK1) is a serine/threonine protein kinase that plays a crucial role in innate immunity. Enhanced TBK1 function is associated with autoimmune diseases and cancer, implicating the potential benefit of therapeutically targeting TBK1. In this article, we examined a recently ident...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Immunol
Päätekijät: Hasan, Maroof, Dobbs, Nicole, Khan, Shaheen, White, Michael A., Wakeland, Edward K., Li, Quan-Zhen, Yan, Nan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: AAI 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4635567/
https://ncbi.nlm.nih.gov/pubmed/26432890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500162
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