Cutting Edge: Increased Autoimmunity Risk in Glycogen Storage Disease Type 1b Is Associated with a Reduced Engagement of Glycolysis in T Cells and an Impaired Regulatory T Cell Function

Glycogen storage disease type 1b (GSD-1b) is an autosomal-recessive disease caused by mutation of glucose-6–phosphate transporter and characterized by altered glycogen/glucose homeostasis. A higher frequency of autoimmune diseases has been observed in GSD-1b patients, but the molecular determinants...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Melis, Daniela, Carbone, Fortunata, Minopoli, Giorgia, La Rocca, Claudia, Perna, Francesco, De Rosa, Veronica, Galgani, Mario, Andria, Generoso, Parenti, Giancarlo, Matarese, Giuseppe
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2017
Assuntos:
Cutting Edge
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5421305/
https://ncbi.nlm.nih.gov/pubmed/28389590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601946
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