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Therapeutic potential of targeting TBK1 in autoimmune diseases and interferonopathies
The serine/threonine protein kinase, TBK1, plays a crucial role as the hub for many innate immune signaling pathways that lead to the induction of type I interferon (IFN) and interferon-stimulated genes (ISGs). Due to its key function in maintaining homeostasis of the immune system, cell survival an...
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| Publicado no: | Pharmacol Res |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5703047/ https://ncbi.nlm.nih.gov/pubmed/27353409 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2016.04.008 |
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