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Cutting Edge: Inhibiting TBK1 by Compound II Ameliorates Autoimmune Disease in Mice

TANK-binding kinase 1 (TBK1) is a serine/threonine protein kinase that plays a crucial role in innate immunity. Enhanced TBK1 function is associated with autoimmune diseases and cancer, implicating the potential benefit of therapeutically targeting TBK1. In this article, we examined a recently ident...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Hasan, Maroof, Dobbs, Nicole, Khan, Shaheen, White, Michael A., Wakeland, Edward K., Li, Quan-Zhen, Yan, Nan
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4635567/
https://ncbi.nlm.nih.gov/pubmed/26432890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500162
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