Ptpn22 and Cd2 Variations Are Associated with Altered Protein Expression and Susceptibility to Type 1 Diabetes in Nonobese Diabetic Mice

By congenic strain mapping using autoimmune NOD.C57BL/6J congenic mice, we demonstrated previously that the type 1 diabetes (T1D) protection associated with the insulin-dependent diabetes (Idd)10 locus on chromosome 3, originally identified by linkage analysis, was in fact due to three closely linke...

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Vydáno v:J Immunol
Hlavní autoři: Fraser, Heather I., Howlett, Sarah, Clark, Jan, Rainbow, Daniel B., Stanford, Stephanie M., Wu, Dennis J., Hsieh, Yi-Wen, Maine, Christian J., Christensen, Mikkel, Kuchroo, Vijay, Sherman, Linda A., Podolin, Patricia L., Todd, John A., Steward, Charles A., Peterson, Laurence B., Bottini, Nunzio, Wicker, Linda S.
Médium: Artigo
Jazyk:Inglês
Vydáno: AAI 2015
Témata:
Immunogenetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4635565/
https://ncbi.nlm.nih.gov/pubmed/26438525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402654
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