ロード中...
Expression of diabetes-associated genes by dendritic cells and CD4 T-cells drives the loss of tolerance in nonobese diabetic mice
In humans and non-obese diabetic (NOD) mice, defects in immune tolerance result in the spontaneous development of type-1-diabetes. Recent studies have ascribed a breakdown in tolerance to dysfunction in regulatory T-cells (Tregs) that is secondary to reduced IL-2 production by T-cells having the NOD...
保存先:
| 主要な著者: | , , , , , , , , , , , |
|---|---|
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2009
|
| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2733871/ https://ncbi.nlm.nih.gov/pubmed/19592648 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900428 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|