NKG2D - RAE-1 receptor-ligand variation does not account for the Natural Killer cell defect in nonobese diabetic mice

Natural Killer (NK) cells from nonobese diabetic (NOD) mice induced with poly I:C in vivo exhibit low cytotoxicity against a range of target cells, but the genetic mechanisms controlling this defect are yet to be elucidated. Defects in the expression of NKG2D and its ligands, the RAE-1 molecules, ha...

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Main Authors: Maier, Lisa M., Howlett, Sarah, Rainbow, Kara, Clark, Jan, Howson, Joanna M.M., Todd, John A., Wicker, Linda S.
Format: Artigo
Jezik:Inglês
Izdano: 2008
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2590656/
https://ncbi.nlm.nih.gov/pubmed/18981127
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