Pharmacologically-induced neurovascular uncoupling is associated with cognitive impairment in mice

There is increasing evidence that vascular risk factors, including aging, hypertension, diabetes mellitus, and obesity, promote cognitive impairment; however, the underlying mechanisms remain obscure. Cerebral blood flow (CBF) is adjusted to neuronal activity via neurovascular coupling (NVC) and thi...

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Veröffentlicht in:J Cereb Blood Flow Metab
Hauptverfasser: Tarantini, Stefano, Hertelendy, Peter, Tucsek, Zsuzsanna, Valcarcel-Ares, M Noa, Smith, Nataliya, Menyhart, Akos, Farkas, Eszter, Hodges, Erik L, Towner, Rheal, Deak, Ferenc, Sonntag, William E, Csiszar, Anna, Ungvari, Zoltan, Toth, Peter
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4635246/
https://ncbi.nlm.nih.gov/pubmed/26174328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2015.162
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