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A Highly Expressed Human Protein, Apolipoprotein B-100, Serves as an Autoantigen in a Subgroup of Patients With Lyme Disease

To discover novel autoantigens associated with Lyme arthritis (LA), we identified T-cell epitopes presented in vivo by human leukocyte antigen (HLA)–DR molecules in patients' inflamed synovial tissue or joint fluid and tested each epitope for autoreactivity. Using this approach, we identified t...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Crowley, Jameson T., Drouin, Elise E., Pianta, Annalisa, Strle, Klemen, Wang, Qi, Costello, Catherine E., Steere, Allen C.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4633766/
https://ncbi.nlm.nih.gov/pubmed/26014802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiv310
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