A Highly Expressed Human Protein, Apolipoprotein B-100, Serves as an Autoantigen in a Subgroup of Patients With Lyme Disease

To discover novel autoantigens associated with Lyme arthritis (LA), we identified T-cell epitopes presented in vivo by human leukocyte antigen (HLA)–DR molecules in patients' inflamed synovial tissue or joint fluid and tested each epitope for autoreactivity. Using this approach, we identified t...

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Vydáno v:J Infect Dis
Hlavní autoři: Crowley, Jameson T., Drouin, Elise E., Pianta, Annalisa, Strle, Klemen, Wang, Qi, Costello, Catherine E., Steere, Allen C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2015
Témata:
Major Articles and Brief Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4633766/
https://ncbi.nlm.nih.gov/pubmed/26014802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiv310
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