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A Highly Expressed Human Protein, Apolipoprotein B-100, Serves as an Autoantigen in a Subgroup of Patients With Lyme Disease

To discover novel autoantigens associated with Lyme arthritis (LA), we identified T-cell epitopes presented in vivo by human leukocyte antigen (HLA)–DR molecules in patients' inflamed synovial tissue or joint fluid and tested each epitope for autoreactivity. Using this approach, we identified t...

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Bibliografiska uppgifter
I publikationen:J Infect Dis
Huvudupphovsmän: Crowley, Jameson T., Drouin, Elise E., Pianta, Annalisa, Strle, Klemen, Wang, Qi, Costello, Catherine E., Steere, Allen C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4633766/
https://ncbi.nlm.nih.gov/pubmed/26014802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiv310
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