A Highly Expressed Human Protein, Apolipoprotein B-100, Serves as an Autoantigen in a Subgroup of Patients With Lyme Disease

To discover novel autoantigens associated with Lyme arthritis (LA), we identified T-cell epitopes presented in vivo by human leukocyte antigen (HLA)–DR molecules in patients' inflamed synovial tissue or joint fluid and tested each epitope for autoreactivity. Using this approach, we identified t...

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Veröffentlicht in:J Infect Dis
Hauptverfasser: Crowley, Jameson T., Drouin, Elise E., Pianta, Annalisa, Strle, Klemen, Wang, Qi, Costello, Catherine E., Steere, Allen C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2015
Schlagworte:
Major Articles and Brief Reports
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4633766/
https://ncbi.nlm.nih.gov/pubmed/26014802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiv310
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