Two rheumatoid arthritis–specific autoantigens correlate microbial immunity with autoimmune responses in joints

In rheumatoid arthritis (RA), immunological triggers at mucosal sites, such as the gut microbiota, may promote autoimmunity that affects joints. Here, we used discovery-based proteomics to detect HLA-DR–presented peptides in synovia or peripheral blood mononuclear cells and identified 2 autoantigens...

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Bibliografische gegevens
Gepubliceerd in:J Clin Invest
Hoofdauteurs: Pianta, Annalisa, Arvikar, Sheila L., Strle, Klemen, Drouin, Elise E., Wang, Qi, Costello, Catherine E., Steere, Allen C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2017
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5531397/
https://ncbi.nlm.nih.gov/pubmed/28650341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI93450
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