Two rheumatoid arthritis–specific autoantigens correlate microbial immunity with autoimmune responses in joints

In rheumatoid arthritis (RA), immunological triggers at mucosal sites, such as the gut microbiota, may promote autoimmunity that affects joints. Here, we used discovery-based proteomics to detect HLA-DR–presented peptides in synovia or peripheral blood mononuclear cells and identified 2 autoantigens...

Full description

Saved in:
Bibliographic Details
Published in:J Clin Invest
Main Authors: Pianta, Annalisa, Arvikar, Sheila L., Strle, Klemen, Drouin, Elise E., Wang, Qi, Costello, Catherine E., Steere, Allen C.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5531397/
https://ncbi.nlm.nih.gov/pubmed/28650341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI93450
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items