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Substance P spinal signaling induces glial activation and nociceptive sensitization after fracture
Tibia fracture in rodents induces substance P (SP)-dependent keratinocyte activation and inflammatory changes in the hindlimb, similar to those seen in complex regional pain syndrome (CRPS). In animal pain models spinal glial cell activation results in nociceptive sensitization. This study tested th...
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| 出版年: | Neuroscience |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4633392/ https://ncbi.nlm.nih.gov/pubmed/26386297 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2015.09.036 |
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