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Substance P spinal signaling induces glial activation and nociceptive sensitization after fracture

Tibia fracture in rodents induces substance P (SP)-dependent keratinocyte activation and inflammatory changes in the hindlimb, similar to those seen in complex regional pain syndrome (CRPS). In animal pain models spinal glial cell activation results in nociceptive sensitization. This study tested th...

詳細記述

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書誌詳細
出版年:Neuroscience
主要な著者: Li, Wen-Wu, Guo, Tian-Zhi, Shi, Xiaoyou, Sun, Yuan, Wei, Tzuping, Clark, David J, Kingery, Wade S
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4633392/
https://ncbi.nlm.nih.gov/pubmed/26386297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2015.09.036
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