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Substance P Signaling Controls Mast Cell Activation, Degranulation, and Nociceptive Sensitization in a Rat Fracture Model of Complex Regional Pain Syndrome
BACKGROUND: Complex regional pain syndrome patients have increased tryptase in the skin of the affected extremity indicating mast cell (MC) accumulation and degranulation, processes known to be mediated by substance P (SP). The dysregulation of SP release from primary afferent neurons is characteris...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3311711/ https://ncbi.nlm.nih.gov/pubmed/22343473 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e31824bb303 |
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