Pentoxifylline attenuates nociceptive sensitization and cytokine expression in a tibia fracture rat model of complex regional pain syndrome

BACKGROUND: Tibia fracture in rats evokes chronic hindpaw warmth, edema, allodynia, and regional osteopenia, a syndrome resembling complex regional pain syndrome (CRPS). Previous studies suggest that the pathogenesis of some of these changes involves an exaggerated regional inflammatory response to...

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Main Authors: Wei, Tzuping, Sabsovich, Ilya, Guo, Tian-Zhi, Shi, Xiaoyou, Zhao, Rong, Li, Wenwu, Geis, Christian, Sommer, Claudia, Kingery, Wade S., Clark, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673487/
https://ncbi.nlm.nih.gov/pubmed/18554967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejpain.2008.04.014
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