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TNF signaling contributes to the development of nociceptive sensitization in a tibia fracture model of complex regional pain syndrome type I

Tibia fracture in rats initiates a cascade of nociceptive, vascular, and bone changes resembling complex regional pain syndrome type I (CRPS I). Previous studies suggest that the pathogenesis of these changes is attributable to an exaggerated regional inflammatory response to injury. We postulated t...

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Detalhes bibliográficos
Main Authors: Sabsovich, Ilya, Guo, Tian-Zhi, Wei, Tzuping, Zhao, Rong, Li, Xiangqi, Clark, David J., Geis, Christian, Sommer, Claudia, Kingery, Wade S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2529181/
https://ncbi.nlm.nih.gov/pubmed/18035493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2007.10.013
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