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Role of Substance P Signaling in Enhanced Nociceptive Sensitization and Local Cytokine Production after Incision

Substance P (SP) signaling facilitates nociceptive sensitization in various inflammatory and chronic pain models and we postulated that SP signaling might also contribute to the development of post-incisional hyperalgesia. These studies used mice with a deletion of the pre-protachykinin A gene (ppt-...

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Detalhes bibliográficos
Main Authors: Sahbaie, Peyman, Shi, Xiaoyou, Guo, Tian-Zhi, Qiao, Yanli, Yeomans, David C., Kingery, Wade S., Clark, J. David
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2746201/
https://ncbi.nlm.nih.gov/pubmed/19660865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2009.06.037
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