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Chronic morphine administration enhances nociceptive sensitivity and local cytokine production after incision
BACKGROUND -: The chronic use of opioids prior to surgery leads to lowered pain thresholds and exaggerated pain levels after these procedures. Several mechanisms have been proposed to explain this heightened sensitivity commonly termed opioid-induced hyperalgesia (OIH). Most of these proposed mechan...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2279109/ https://ncbi.nlm.nih.gov/pubmed/18294378 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-4-7 |
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