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JNK-Bcl-2/Bcl-xL-Bax/Bak Pathway Mediates the Crosstalk between Matrine-Induced Autophagy and Apoptosis via Interplay with Beclin 1

Autophagy is associated with drug resistance which has been a threat in chemotherapy of hepatocellular carcinoma (HCC). The interconnected molecular regulators between autophagy and apoptosis serve as switching points critical to the ultimate outcome of the cell. Our study was performed to investiga...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Yang, Jiong, Yao, Shukun
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4632824/
https://ncbi.nlm.nih.gov/pubmed/26516844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms161025744
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