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JNK-Bcl-2/Bcl-xL-Bax/Bak Pathway Mediates the Crosstalk between Matrine-Induced Autophagy and Apoptosis via Interplay with Beclin 1

Autophagy is associated with drug resistance which has been a threat in chemotherapy of hepatocellular carcinoma (HCC). The interconnected molecular regulators between autophagy and apoptosis serve as switching points critical to the ultimate outcome of the cell. Our study was performed to investiga...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Yang, Jiong, Yao, Shukun
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4632824/
https://ncbi.nlm.nih.gov/pubmed/26516844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms161025744
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