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JNK-Bcl-2/Bcl-xL-Bax/Bak Pathway Mediates the Crosstalk between Matrine-Induced Autophagy and Apoptosis via Interplay with Beclin 1

Autophagy is associated with drug resistance which has been a threat in chemotherapy of hepatocellular carcinoma (HCC). The interconnected molecular regulators between autophagy and apoptosis serve as switching points critical to the ultimate outcome of the cell. Our study was performed to investiga...

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書目詳細資料
發表在:Int J Mol Sci
Main Authors: Yang, Jiong, Yao, Shukun
格式: Artigo
語言:Inglês
出版: MDPI 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4632824/
https://ncbi.nlm.nih.gov/pubmed/26516844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms161025744
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