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CRISPR/Cas9-Mediated Rapid Generation of Multiple Mouse Lines Identified Ccdc63 as Essential for Spermiogenesis

Spermatozoa are flagellated cells whose role in fertilization is dependent on their ability to move towards an oocyte. The structure of the sperm flagella is highly conserved across species, and much of what is known about this structure is derived from studies utilizing animal models. One group of...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Young, Samantha A. M., Miyata, Haruhiko, Satouh, Yuhkoh, Kato, Hirotaka, Nozawa, Kaori, Isotani, Ayako, Aitken, R. John, Baker, Mark A., Ikawa, Masahito
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4632774/
https://ncbi.nlm.nih.gov/pubmed/26501274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms161024732
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