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Revolutionizing male fertility factor research in mice by using the genome editing tool CRISPR/Cas9

BACKGROUND: Reproductive research is quintessential in understanding not only the cause of infertility, but also for creating family planning tools. The knockout (KO) system approach is conducive to discovering genes that are essential for fertility in mice. However, in vivo research has been limite...

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Bibliographische Detailangaben
Veröffentlicht in:Reprod Med Biol
Hauptverfasser: Abbasi, Ferheen, Miyata, Haruhiko, Ikawa, Masahito
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5768971/
https://ncbi.nlm.nih.gov/pubmed/29371815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/rmb2.12067
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