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Combining Protein and Strain Engineering for the Production of Glyco-Engineered Horseradish Peroxidase C1A in Pichia pastoris

Horseradish peroxidase (HRP), conjugated to antibodies and lectins, is widely used in medical diagnostics. Since recombinant production of the enzyme is difficult, HRP isolated from plant is used for these applications. Production in the yeast Pichia pastoris (P. pastoris), the most promising recomb...

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Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Capone, Simona, Ćorajević, Lejla, Bonifert, Günther, Murth, Patrick, Maresch, Daniel, Altmann, Friedrich, Herwig, Christoph, Spadiut, Oliver
Format: Artigo
Langue:Inglês
Publié: MDPI 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4632689/
https://ncbi.nlm.nih.gov/pubmed/26404235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms161023127
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