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Production of a recombinant peroxidase in different glyco-engineered Pichia pastoris strains: a morphological and physiological comparison

BACKGROUND: The methylotrophic yeast Pichia pastoris is a common host for the production of recombinant proteins. However, hypermannosylation hinders the use of recombinant proteins from yeast in most biopharmaceutical applications. Glyco-engineered yeast strains produce more homogeneously glycosyla...

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Detalhes bibliográficos
Publicado no:Microb Cell Fact
Main Authors: Pekarsky, Alexander, Veiter, Lukas, Rajamanickam, Vignesh, Herwig, Christoph, Grünwald-Gruber, Clemens, Altmann, Friedrich, Spadiut, Oliver
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6260843/
https://ncbi.nlm.nih.gov/pubmed/30474550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-018-1032-6
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