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Combining Protein and Strain Engineering for the Production of Glyco-Engineered Horseradish Peroxidase C1A in Pichia pastoris

Horseradish peroxidase (HRP), conjugated to antibodies and lectins, is widely used in medical diagnostics. Since recombinant production of the enzyme is difficult, HRP isolated from plant is used for these applications. Production in the yeast Pichia pastoris (P. pastoris), the most promising recomb...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Capone, Simona, Ćorajević, Lejla, Bonifert, Günther, Murth, Patrick, Maresch, Daniel, Altmann, Friedrich, Herwig, Christoph, Spadiut, Oliver
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4632689/
https://ncbi.nlm.nih.gov/pubmed/26404235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms161023127
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