En bloc substitution of the Src homology region 2 domain activates the transforming potential of the c-Abl protein tyrosine kinase.

Src homology region 2 (SH2) domains are present in many proteins involved in signal transduction. In nonreceptor protein tyrosine kinases the SH2 domain has been implicated in regulation of tyrosine kinase activity and in mediating interactions involved in downstream signaling. Different SH2 domains...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Muller, A J, Pendergast, A M, Parmar, K, Havlik, M H, Rosenberg, N, Witte, O N
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1993
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC46319/
https://ncbi.nlm.nih.gov/pubmed/7682703
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