En bloc substitution of the Src homology region 2 domain activates the transforming potential of the c-Abl protein tyrosine kinase.

Src homology region 2 (SH2) domains are present in many proteins involved in signal transduction. In nonreceptor protein tyrosine kinases the SH2 domain has been implicated in regulation of tyrosine kinase activity and in mediating interactions involved in downstream signaling. Different SH2 domains...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Muller, A J, Pendergast, A M, Parmar, K, Havlik, M H, Rosenberg, N, Witte, O N
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1993
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC46319/
https://ncbi.nlm.nih.gov/pubmed/7682703
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