Evidence for regulation of the human ABL tyrosine kinase by a cellular inhibitor.

Phosphotyrosine cannot be detected on normal human ABL protein-tyrosine kinases, but activated oncogenic forms of the human ABL protein are phosphorylated on tyrosine in vivo. Activation of ABL can occur by substitution of the ABL first exon with breakpoint cluster region (BCR) sequences or by delet...

Descrizione completa

Dettagli Bibliografici

Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Pendergast, A M, Muller, A J, Havlik, M H, Clark, R, McCormick, F, Witte, O N
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1991
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51991/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1712111/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.13.5927
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!