Evidence for regulation of the human ABL tyrosine kinase by a cellular inhibitor.

Phosphotyrosine cannot be detected on normal human ABL protein-tyrosine kinases, but activated oncogenic forms of the human ABL protein are phosphorylated on tyrosine in vivo. Activation of ABL can occur by substitution of the ABL first exon with breakpoint cluster region (BCR) sequences or by delet...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Pendergast, A M, Muller, A J, Havlik, M H, Clark, R, McCormick, F, Witte, O N
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51991/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1712111/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.13.5927
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