Evidence for regulation of the human ABL tyrosine kinase by a cellular inhibitor.
Phosphotyrosine cannot be detected on normal human ABL protein-tyrosine kinases, but activated oncogenic forms of the human ABL protein are phosphorylated on tyrosine in vivo. Activation of ABL can occur by substitution of the ABL first exon with breakpoint cluster region (BCR) sequences or by delet...
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| Gepubliceerd in: | Proc Natl Acad Sci U S A |
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| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
National Academy of Sciences
1991
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51991/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1712111/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.13.5927 |
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