Preclinical Evaluations To Identify Optimal Linezolid Regimens for Tuberculosis Therapy

Linezolid is an oxazolidinone with potent activity against Mycobacterium tuberculosis. Linezolid toxicity in patients correlates with the dose and duration of therapy. These toxicities are attributable to the inhibition of mitochondrial protein synthesis. Clinically relevant linezolid regimens were...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:mBio
Egile Nagusiak: Brown, Ashley N., Drusano, George L., Adams, Jonathan R., Rodriquez, Jaime L., Jambunathan, Kalyani, Baluya, Dodge L., Brown, David L., Kwara, Awewura, Mirsalis, Jon C., Hafner, Richard, Louie, Arnold
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Microbiology 2015
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4631805/
https://ncbi.nlm.nih.gov/pubmed/26530386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01741-15
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